‘Undetectable equals untransmissible’, or U=U, refers to the fact that people who take antiretroviral therapy for HIV daily as prescribed, and who achieve and maintain an undetectable viral load, cannot sexually transmit the virus to an HIV-negative partner.

U=U: ASHM guidance for healthcare professionals draws on the latest evidence to inform healthcare providers about U=U and provides recommendations for speaking about U=U to all patients, including those newly diagnosed with HIV.

Key changes in this third edition of the guidance include: