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Post-Exposure Prophylaxis after Non-Occupational and Occupational Exposure to HIV: Australian Guidelines

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The updated post-exposure prophylaxis (PEP) guidelines combine non-occupational and occupational HIV exposure in a single document for the first time

PEP Guidelines August 2016.JPGAugust 2016:  The Second edition of the Post-Exposure Prophylaxis after Non-Occupational and Occupational Exposure to HIV: Australian National Guidelines is now available.

These guidelines outline the management of individuals who have been exposed (or suspect they have been exposed) to HIV in non-occupational and occupational settings. There are currently no data from randomised controlled trials of the use of post-exposure prophylaxis (PEP) and evidence for use has been extrapolated from animal data, mother to child transmission, occupational exposure and small prospective studies of PEP regimens in HIV-negative men. Accordingly, assumptions are made about the direction of management.

Every presentation for PEP should be assessed on a case-by-case basis, balancing the potential harms
and benefits of treatment.

Recommendations following non-occupational exposure have been updated, and information about PEP in the context of pre-exposure prophylaxis (PrEP), PEP and children, renal disease, and gender identity and history has been added.


Download the resource

Post-Exposure Prophylaxis after Non-Occupational and Occupational Exposure to HIV: Australian National Guidelines


Related documents

Updates to the supplementary documents, as well as a navigable website for the guidelines, will soon be available. At present, the 2013 literature review and Checklist are still available for your convenience, linked below.

PEP Checklist (2013)

Literature Review (2013)


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